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09 February 2012

Answer to Question #1961 Submitted to "Ask the Experts"

Category: Radiation Workers

The following question was answered by an expert in the appropriate field:

I am a radiologic technologist. My question is about radioactive iodine (¹³¹I). I have Graves' disease. Do you have any information on the whole-body dose from radioactive iodine (RAI) treatment and the dose to individual organs? I realize that this is dependent on the dose of RAI given to the patient. However any statistics using any dose would be appreciated.

Therapy for Graves' disease usually involves administration of 10-20 mCi (370-740 MBq) of radioactive iodine (¹³¹I) as sodium iodide. This is designed to give a rather high radiation dose to the thyroid (which will vary considerably, depending on thyroid uptake and mass at the time of the exam) and lower doses to other organs (about 15-30 rad [150-300 mGy] to urinary bladder and stomach, 2-5 rad [20-50 mGy] to gonads and marrow). A "whole body" dose is not usually discussed in this application, as the dose is nonuniform, and it is more appropriate to discuss individual organ doses. Michael G. Stabin, PhD, CHP Assistant Professor of Radiology and Radiological Sciences

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